Patients with NMDAR encephalitis and controls had similar microbiome profiles of the gut microbiota
NMDAR 腦炎患者和對照組具有相似的腸道微生物群概況。
Patients in the acute encephalitis stage (n = 8) showed significant differences in the numbers of Clostridium XVIII, Clostridium IV, Oscillibacter, Prevotella, and Blautia;
急性腦炎期患者 (n = 8) 的梭狀芽孢桿菌 XVIII、梭狀芽孢桿菌 IV、振盪桿菌、普雷沃氏菌和布勞氏桿菌的數量存在顯著差異;
Prominent dysbiosis in the gut microbiome of patients with anti-NMDAR encephalitis was found.
發現抗 NMDAR 腦炎患者的腸道微生物組存在明顯的生態失調。
Our primary findings showed that the overall species richness (alpha diversity indexes) of the microbiota was higher in patients than in controls (P < 0.05).
我們的主要研究結果表明,患者微生物群的總體物種豐富度(α 多樣性指數)高於對照組(P < 0.05)。
Additionally, our results showed that all subgroups had a distinct bacterial species, with an increase in the genus Fusobacterium in the acute phase group and the genera Streptococcus and Parabacteroides in patients with relapse.
此外,我們的結果顯示所有亞組都有不同的細菌種類,急性期組梭桿菌屬增加,復發患者鏈球菌屬和副桿菌屬增加。